In Current Controversies in Bone Marrow Transplantation, Brian J. Bolwell and a distinguished team of transplant physicians critically review and interpret twenty-one key clinical challenges in bone marrow/hematopoietic cell transplantation, and offer their best personal recommendations for treatment. Topics range from transplant strategies to complications of bone marrow transplantation, including a discussion of the indications, benefits, and the risks for a variety of leukemias, lymphomas, and solid tumors. The authors debate such contentious issues as the appropriateness of transplants in older patients, how many stem cells are sufficient for engraftment, and the pros and cons of umbilical cord blood transplantation. They also discuss such key points as the role of a busulfan-based preparative regimen versus total body irradiation in both children and adults, and the indications, outcomes, and limitations of autologous transplantation for ovarian cancer, metastatic breast cancer, inflammatory breast cancer, and germ cell tumors. Common clinical management problems of transplant patients are also addressed.
Up-to-date and clinically focused, Current Controversies in Bone Marrow Transplantation represents a snapshot of many current issues in transplantation as we enter the new millennium. The book offers clinical oncologists, hematology/oncology fellows in training, and residents in internal medicine today's best ready reference and management guide for all their critical oncologic problems arising from the use of bone marrow/stem cell transplantation.
